| July 14 (Tue) | 1st day |
|---|---|
| Symposium 1 [KIT] Unraveling Disease Pathogenesis through In Vivo and Organoid Models |
14:00–15:40 Halla Hall A |
| Organizer | Haengdueng Jeong Hanyang University |
| Establishing Gastric Cancer Cell Lines Transplantable into C57BL/6 Mice and Utilizing their Sphere Formation | Nomura Sachiyo University of Hoshi |
| Epithelial WNT Secretion Drives Niche Escape of Developing Gastric Cancer | Ji-Hyun Lee IBS |
| Hybrid Identity of Incomplete Intestinal Metaplasia in the Stomach | Bogun Jang Jeju National University |
| Brain Organoids and Microglia for Bridging Disease Models to Mechanisms | Jong-Chan Park Sungkyunkwan University |
| Chair |
Haengdueng Jeong Hanyang University Ji-Hyun Lee IBS |
| July 14 (Tue) | 1st day |
|---|---|
| Symposium 2 Development and Application of Humanized Mice for Biomedical Research |
14:00–15:40 Halla Hall B |
| Organizer | Dae-Yeul Yu GH-bio |
| Humanized Mouse Platforms for Cancer Immunotherapy: From Human Immune System Reconstitution to Preclinical Evaluation of Therapeutics | Ki-Young Lee Sungkyunkwan University |
| Fine-Tuning Signal Strength in CD5 CAR-NK Cells for Targeted T cell Cancer Therapy | Tae-Don Kim Yonsei University |
| Reprogramming, Not Suppressing: Immune Rebalancing as a Therapeutic Strategy in Humanized Models of GVHD and IBD | Kyung-Rok Yu Seoul National University |
| A Scalable Two-Step Genome Editing Strategy for Generating Full-Length Gene-Humanized Mice at Diverse Genomic Loci | Manabu Ozawa University of Tokyo |
| Chair |
Dae-Yeul Yu GH-bio |
| July 14 (Tue) | 1st day |
|---|---|
| Symposium 3 (KLAT Education I) From Animals to Answers: Practical Experimental Research |
14:00–15:40 Samda Hall |
| Organizer | Young-Shin Joo The Catholic University of Korea |
| Introduction to Aseptic Surgery: Concepts and Practice |
Ji Hyun Kim (Former)Seoul St. Mary’s Hospital |
| Essentials of Mouse Surgery for Beginners: Key Techniques, Precautions, and Basic Procedures |
Seung-Ho Heo Asan Medical Center |
| Practical Approaches to Mouse and Rat Necropsy and Histopathology in Laboratory Animal Research |
Sun Shin Yi Konkuk University |
| Chair |
Ji-Young Kim Ewha Womans University |
| July 14 (Tue) | 1st day |
|---|---|
| Symposium 4 [K-MEDI hub / KBIOHealth] Rebuilding Brain and Gut: Stem Cells, Organoids, and Humanized Disease Models |
16:00–17:40 Halla Hall A |
| Organizer |
Kyoung-Jin Oh
KRIBB
Se Jin Jeon Hallym University |
| Humanizing the Mouse Brain with iPSC-Derived Microglia |
Yongjin Yoo Korea University |
| Gastric Cell Lineage Plasticity Drives Response to Injury and Carcinogenesis |
James R. Goldenring Vanderbilt University Medical Center |
| Brain-on-a-Chip Platforms for Studying Human Brain Diseases |
Hong Nam Kim KIST |
| hPSC-Derived Intestinal Organoids as Predictive Translational Platforms for Preclinical Efficacy and Safety Assessment |
Hana Lee KRIBB |
| Chair |
Joon-Suk Park K-MEDI hub Joong Hyun Kim KBIOHealth |
| July 14 (Tue) | 1st day |
|---|---|
|
Symposium 5 Stem Shift: Organoid and MPS for Angiogenesis |
16:00–17:40 Halla Hall B |
| Organizer | Jaejin Cho Seoul National University |
| Vascularization of Neuromuscular Organoids through a Minimalist Approach to Early Symmetry Breaking | Woong Sun Korea University |
| Microphysiological Systems for Engineering Human Vascular Barriers |
Song Ih Ahn KAIST |
| Angiogenesis in Tissue Reforming Technology Platform for Therapeutic Organoid |
Jaejin Cho Seoul National University |
| On-Demand Drug Delivery System Driven by Ultrasonic Actuator |
Yuta Kurashina Tokyo University of Agriculture and Technology |
| Chair |
Jaejin Cho Seoul National University |
| July 14 (Tue) | 1st day |
|---|---|
|
Symposium 6 (KALAS-JALAS) Next-Generation Laboratory Animal Science: AI, NAMs, and One Health Convergence |
16:30-18:10 Samda Hall |
| Organizer | Sun Shin Yi Konkuk University |
| Organoid-Based Modeling of Regenerative Plasticity: Unveiling the Role of Fetal Reprogramming in Tissue Repair |
Hyung-Sik Kim Pusan National University |
| Alveolar Organoids as a Versatile NAM Platform for Respiratory and Occupational Lung Disease Applications |
Se-Ran Yang Kangwon National University |
| AI-Enabled Digital Phenotyping in Laboratory Rats Using Earable Sensors and Machine Learning |
Ryota Tochinai University of Tokyo |
| SPF: A Clean Yet Constrained Microbial World |
Fumio Ike RIKEN BRC |
| Chair |
Se-Ran Yang Kangwon National University Seiya Mizuno University of Tsukuba |
| July 15 (Wed) | 2nd day |
|---|---|
|
Symposium 7 [KMPC] Recent Advances in Rat Genome Research: Global and Domestic Trends |
09:40–11:20 Halla Hall A |
| Organizer | Jun-Won Yun Seoul National University |
| Advancing Rat-Based Biomedical Research in Korea: The Rat Resource Center and Future Perspectives |
Jun-Won Yun Seoul National University |
| Advancing Rat Genome Research through NBRP-Rat in Japan and Recent Genome Editing Technologies |
Kazuto Yoshimi Kyoto University |
| Assisted Reproductive Technologies in Rats: From Gamete Cryopreservation to Embryo Transfer |
Tae Min Kim Seoul National University |
| Identification of Rat Blood Group Antigens |
Hee Young Kim Yonsei University |
| Chair | Jun-Won Yun Seoul National University Tae Min Kim Seoul National University |
| July 15 (Wed) | 2nd day |
|---|---|
| Symposium 8 Neural Circuits in Organ Crosstalk and Neurodegeneration |
09:40–11:20 Halla Hall B |
| Organizer |
Sun Shin Yi
Konkuk University
Chan Hee Lee Hallym University |
| A Spatial and Projection-Based Transcriptomic Atlas of Paraventricular Hypothalamic Cell Types |
Jon Resch University of Iowa Carver |
| A Hypothalamus-Adipose Neural Circuit Mediates Metabolic Benefits of Transient Stress |
Chan Hee Lee Hallym University |
| Can Artificial Intelligence Detect Neurodegeneration in Blood? A Machine Learning-Based NAMs Strategy for Early Prediction of CCDS |
Sun Shin Yi Konkuk University |
| Epigenetic Remodeling of the Inflamed Gut and Microbe-Mediated Control of the Gut-Brain Axis |
Kyung Ku Jang Yonsei University |
| Chair |
Sun Shin Yi Konkuk University Chan Hee Lee Hallym University |
| July 15 (Wed) | 2nd day |
|---|---|
|
Symposium 9 [AAALAC International] Filling the Gaps for the Institutions Seeking Accreditation |
09:40–11:20 Samda Hall |
| Organizer | Young-Shin Joo The Catholic University of Korea |
| Overview and Update of AAALAC International Accreditation Program |
Montip Gettayacamin AAALAC International |
| Step 1: Applying and Attaining Accreditation in Commercial Research Environment |
Jungmin Lee Samsung Medical Center |
| Step 2: Preparing the Program Description and Site Visit | Young-Shin Joo The Catholic University of Korea |
| Step 3: Expectation of the Post Site visit Communication and Council Deliberations | Seung Hyeok Seok Seoul National University |
| Chair |
Seung Hyeok Seok Seoul National University |
| July 15 (Wed) | 2nd day |
|---|---|
| Plenary Lecture 1 [KMPC] | 11:40–12:30 Halla Hall A |
| Organizer | Kyoungmi Kim Seoul National University |
| Advances in Reproductive Engineering: From Gametes to Offspring at RIKEN BioResource Research Center |
Atsuo Ogura RIKEN BRC |
| Chair |
Je Kyung Seong Seoul National University |
| July 15 (Wed) | 2nd day |
|---|---|
| Symposium 10 [KMPC] Microbiome Research Using Animal Models |
14:30–16:10 Halla Hall A |
| Organizer |
Seongbeom Cho
Seoul National University
Eunha Kim Korea University |
| The Nasal Microbiome Shape Tissue Specific Immunity to Maintain Respiratory Health and Disease | Ho-Keun Kwon Yonsei University |
| Microbiome Alteration during Domestication of Wild Mouse | Je Kyung Seong Seoul National University |
| Microbiome Communities and Antitumor Immune Modulation | Yunjae Kim GIST |
| Neuronal and Hormonal Gut-Brain Pathways Underlying Physiological Adaptations in Drosophila | Yangkyun Oh Ewha Womans University |
| Chair |
Seongbeom Cho Seoul National University Eunha Kim Korea University |
| July 15 (Wed) | 2nd day |
|---|---|
| Symposium 11 [NIFDS] Discoveries from Korl(Korean Laboratory Animal) Resources : New Phenotypes in Disease Model Animals |
14:30–16:10 Halla Hall B |
| Organizer | Rheeda Lee NIFDS |
| Overview of Korl(Korean Laboratory Animal) and Derived Resources | Ji Hyeon Seok NIFDS |
| Characterization of FVB/N-C3em1Hlee/Korl Mice as Novel Disease Models for Chronic Constipation and Age-Related Macular Degeneration | Dae Youn Hwang Pusan National University |
| Application of Leptin-Knockout ob/ob Mice as a Diabetes-Obesity Model for Evaluating 2,5-Hexanedione-Induced Neurotoxicity | Min-Sun Kim Sunchon National University |
| Alzheimer’s Disease Mouse Models Reveal the Therapeutic Potential of ULK1-Rab9-Dependent Alternative Mitophagy | Jeanho Yun Dong-A University |
| Chair |
Rheeda Lee NIFDS |
| July 15 (Wed) | 2nd day |
|---|---|
| Symposium 12 [AAALAC International] Small Group Discussion |
14:30-16:10 Samda Hall |
| Organizer |
Young-Shin Joo The Catholic University of Korea |
| Open Q&A Session: Filling the Gaps by Sharing Experience with Accredited Institutions |
Group 1. Government
Seung Hyeok Seok (Seoul National University)
Group 2. Commercial
Young-Shin Joo (The Catholic University of Korea)
Group 3. Academia & Hospital
Jungmin Lee (Samsung Medical Center)
Group 4. GLP & CRO
Hae-Jin Yoon (NST)
Group 5. Others
Montip Gettayacamin (AAALAC International)
Insook Yang (Yonsei University Health System) |
| Preparing for Accreditation: Lessons Learned from Experience | Hae-Jin Yoon NST |
| Open Q&A Session: Filling the Gaps by Sharing Tips for New Applicants |
Group 1. Government
Seung Hyeok Seok (Seoul National University)
Group 2. Commercial
Young-Shin Joo (The Catholic University of Korea)
Group 3. Academia & Hospital
Jungmin Lee (Samsung Medical Center)
Group 4. GLP & CRO
Hae-Jin Yoon (NST)
Group 5. Others
Montip Gettayacamin (AAALAC International)
Insook Yang (Yonsei University Health System) |
| Chair |
Montip Gettayacamin AAALAC International |
| July 15 (Wed) | 2nd day |
|---|---|
| Academy Award Presentation | 16:20-17:00 Halla Hall A |
| Signed-Network-Based Analytical Framework Integrating Large-Scale Literature Mining Identifies Underexplored Molecular Regulators of Liver Fibrosis | Wonhyo Seo Ewha Womans University |
| Tumor Plasticity and Microenvironmental Reprogramming in Cancer Progression | Jeong-Seok Nam GIST |
| Chair |
Ki Taek Nam Yonsei University |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 13 [SNUH-MMNC] The Evolution of Neuroscience and AI-Driven Behavioral Analysis Using Marmosets |
09:30-11:10 Halla Hall A |
| Organizer | Byeong-Cheol Kang Seoul National University |
| Longitudinal Circadian - Behavioral Profiling in Marmosets: Toward Early Biomarkers of Autism Spectrum Disorder | Kyoung-Sun Lee KBIOHealth |
| Dynamic Social Vision in Marmosets: From Natural Behavior to Neural Mechanisms | Soo Hyun Park KAIST |
| Behavioral and Multimodal Phenotyping in Neurodegenerative Disease Model Marmosets | Erika Sasaki CIEM |
| Vocal Communication Behaviors of Marmoset | Xiaoqin Wang Tsinghua University |
| Chair |
Byeong-Cheol Kang Seoul National University |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 14 AI-Driven Radiomics for Next-Generation Immune and Anti-Aging Translational Modeling |
09:30–11:10 Halla Hall B |
| Organizer | Seung Hyeok Seok Seoul National University |
| Developing Radiomics Tools for Sharks as an Emerging Unconventional Animal Model for Antitumor and Anti-Aging Research | Sang Wha Kim Kangwon National University |
| Single-Cell Pathway Remodeling Associated with Butyrate-Induced Brain Imaging Alterations | Mohan Huang Tung Wah College |
| PET/CT Radiomics Reveals Convergent Brain Regional Alterations Following Butyrate and Gut Microbiota Interventions | Adams Hei Long Yuen Tung Wah College |
| Murine Models Identifying Immune Determinants of Radiation Therapy Resistance | Seung Hyeok Seok Seoul National Univeristy |
| Chair |
Jung Joo Hong KRIBB |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 15 (IACUC) Refinement in Practice: Scientific Pain Management and the Dilemma of Analgesic Use |
09:30–11:10 Samda Hall |
| Organizer | Jong-Hwan Park Chonnam National University |
| Regulatory Perspectives and Guidelines on Pain and Distress in Animal Research | Jinsoo Lee Chungnam National University |
| Guidelines for Analgesic Use: Considerations for Species and Experimental Protocols | Hwan Kim IBS |
| Scientific Validity of Analgesic Use: Understanding the Impact on Experimental Outcomes | Ji-Yeon Hwang Seoul National University Bundang Hospital |
| Chair |
Jong-Hwan Park Chonnam National University |
| July 16 (Thu) | 3rd day |
|---|---|
| Plenary Lecture 2 [Yonsei NRL2.0] | 11:30–12:20 Halla Hall A |
| Organizer | Won Dong Lee Yonsei University |
| Microengineered Mimicry of Human Health and Disease | Dan Dongeun Huh University of Pennsylvania |
| Chair |
Won Dong Lee Yonsei University |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 16 [AMC-CHOICE] Advances in Neuroscience Research: Global and Domestic Trends for Neurotherapeutics |
14:30–16:10 Halla Hall A |
| Organizer | Sang-Yeob Kim Asan Medical Center |
| Opposing Opioid Actions in the Brainstem Dissociate Analgesia and Seeking | Sung Han Salk Institute for Biological Studies |
| Small-Animal Nuclear Medicine Imaging in Brain Disease Models | Seog-Young Kim Asan Medical Center |
| Utilization of Preclinical MRI in Brain Disease Models | Dong-Cheol Woo Asan Medical Center |
| Optical Imaging Approaches for Neurological Disorders: From Bench to Bedside | Sang-Yeob Kim Asan Medical Center |
| Chair |
Sang-Yeob Kim Asan Medical Center |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 17 [KRIBB] Regulatory Mechanisms of Hepatic Metabolic Reprogramming in Liver Disease |
14:30–16:10 Halla Hall B |
| Organizer | Wonhyo Seo Ewha Womans University |
| Targeting Isoform Specific Metabolic Enzymes in Liver Disease | Hyunsoo Rho Ewha Womans Univeristy |
| Casp2: The New Hepatic Lipid Regulator | Ju Youn Kim Hanyang University |
| MicroRNA Mediated Reprogramming of the Steatotic Liver in MASLD | Yoon Mee Yang Sungkyunkwan University |
| Hepatocyte TET1 Promotes MASH Fibrosis through GPNMB | Junjie Yu China Pharmaceutical University |
| Chair |
Ki-Hoan Nam KRIBB Seung-Jin Kim Kangwon National University |
| July 16 (Thu) | 3rd day |
|---|---|
| Symposium 18 (KLAT Education II) Know Your Animals: Biology, Behavior, and Better Care |
14:30–16:10 Samda Hall |
| Organizer | Young-Shin Joo The Catholic University of Korea |
| Understanding Laboratory Rabbits: Characteristics, Husbandry, and Experimental Applications | Insook Yang Yonsei University Health System |
| Application of Minipig to Nonclinical Study (From General Introduction to Experiment) | Han Na Suh KIT |
| Understanding Nonhuman Primates for Better Care | Kyoung-Sun Lee KBIOHealth |
| 기술원 QUIZ | |
| Chair |
Seung Hyun Oh Seoul National University Young-Shin Joo The Catholic University of Korea |
